2. Inhibitory Antibodies
  3. Naxitamab

Naxitamab  (Synonyms: 那昔妥单抗; Naxitamab-gqgk; Humanized 3F8; Hu3F8)

目录号: HY-P99206 纯度: 98.13%
COA

摩尔计算器

Naxitamab (Hu3F8) 是一种人源化单克隆抗体，靶向二氮冈糖苷 GD2 (hu3F8)。Naxitamab 可用于神经母细胞瘤、骨肉瘤和其他 GD2 阳性癌症的研究。

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CAS No. : 1879925-92-4

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规格 价格 是否有货 数量
1 mg ￥2000
In-stock
5 mg ￥5750
In-stock
10 mg ￥9500
In-stock
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100 mg   询价  

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Customer Review

Naxitamab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Naxitamab (Hu3F8) is a humanized monoclonal antibody targeting the disialoganglioside GD2. Naxitamab can be used in research of neuroblastoma, osteosarcoma and other GD2-positive cancers[1].

同型

Human IgG1 kappa
推荐同型对照抗体
种属

Chimeric
体外研究
(In Vitro)

Naxitamab (Hu3F8; 72 h) has cytotoxicity against neuroblastoma cell line LAN-1 with an EC50 value of 5.1 μg/mL[1].
Naxitamab (0.1-1 μg/mL; 4 h; peripheral blood mononuclear cells (PBMC) and polymorphonuclear leukocytes (PMN)) has antibody-dependent cell-mediated cytotoxic effects (ADCC)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Naxitamab 相关抗体:
体内研究
(In Vivo)

Naxitamab (Hu3F8; 100 mg/kg; i.v.; twice a week, for 4 weeks; athymic nude mice with LAN-1 xenografts) inhibits tumor growth in neuroblastoma xenografts[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female athymic nude mice with LAN-1 xenografts[1]
Dosage: 100 mg/kg
Administration: Intravenous injection; twice a week, for 4 weeks
Result: Inhibited tumor growth and prolonged the survival time.
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

那昔妥单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
纯度 & 产品资料
参考文献

Naxitamab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Naxitamab1879925-92-4Naxitamab-gqgk Humanized 3F8 Hu3F8那昔妥单抗Othershumanized monoclonal antibodyLAN-1 cellsneuroblastomaosteosarcomaanticancerantibody-dependent cell-mediated cytotoxicInhibitorinhibitorinhibit

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